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dc.contributorMwacharo, Joramen_US
dc.contributorMwaura, Stephenen_US
dc.contributorNjuguna, Joyceen_US
dc.contributorNzuki, Inostersen_US
dc.contributorKinyanjui, Peter W.en_US
dc.contributorGithaka, Naftalyen_US
dc.contributorHeyne, Heloiseen_US
dc.contributorHanotte, Olivieren_US
dc.contributorSkilton, Roberten_US
dc.contributorBishop, Richard P.en_US
dc.creatorKanduma, Esther G.en_US
dc.identifier.citationEsther G. Kanduma, Joram Mwacharo, Stephen Mwaura, Joyce Njuguna, Inosters Nzuki, Peter W. Kinyanjui, Naftaly Githaka, Heloise Heyne, Olivier Hanotte, Robert Skilton, Richard P. Bishop. (26/1/2016). Multi-locus genotyping reveals absence of genetic structure in field populations of the brown ear tick (Rhipicephalus appendiculatus) in Kenya. Ticks and Tick-borne Diseases, 7 (1), pp. 26-35.en_US
dc.description.abstractRhipicephalus appendiculatus is an important tick vector of several pathogens and parasitizes domestic and wild animals across eastern and southern Africa. However, its inherent genetic variation and population structure is poorly understood. To investigate whether mammalian host species, geographic separation and resulting reproductive isolation, or a combination of these, define the genetic structure of R. appendiculatus, we analyzed multi-locus genotype data from 392 individuals from 10 geographic locations in Kenya generated in an earlier study. These ticks were associated with three types of mammalian host situations; (1) cattle grazing systems, (2) cattle and wildlife co-grazing systems (3) wildlife grazing systems without livestock. We also analyzed data from 460 individuals from 10 populations maintained as closed laboratory stocks and 117 individuals from five other species in the genus Rhipicephalus. The pattern of genotypes observed indicated low levels of genetic differentiation between the ten field populations (FST = 0.014 ± 0.002) and a lack of genetic divergence corresponding to the degree of separation of the geographic sampling locations. There was also no clear association of particular tick genotypes with specific host species. This is consistent with tick dispersal over large geographic ranges and lack of host specificity. In contrast, the 10 laboratory populations (FST = 0.248 ± 0.015) and the five other species of Rhipicephalus (FST = 0.368 ± 0.032) were strongly differentiated into distinct genetic groups. Some laboratory bred populations diverged markedly from their field counterparts in spite of originally being sampled from the same geographic locations. Our results demonstrate a lack of defined population genetic differentiation in field populations of the generalist R. appendiculatus in Kenya, which may be a result of the frequent anthropogenic movement of livestock and mobility of its several wildlife hosts between different locations.en_US
dc.sourceTicks and Tick-borne Diseases;7,(2016) Pagination 26,35en_US
dc.titleMulti-locus genotyping reveals absence of genetic structure in field populations of the brown ear tick (Rhipicephalus appendiculatus) in Kenyaen_US
dc.typeJournal Articleen_US
cg.creator.idMwacharo, Joram: 0000-0001-6981-8140en_US
cg.creator.idHanotte, Olivier: 0000-0002-2877-4767en_US
cg.contributor.centerInternational Livestock Research Institute - ILRIen_US
cg.contributor.centerInternational Center for Agricultural Research in the Dry Areas - ICARDAen_US
cg.contributor.centerBiosciences Eastern and Central Africa - BeCAen_US
cg.contributor.centerUniversity of Nairobi - UONBIen_US
cg.contributor.centerAgricultural Research Council - ARC-LNRen_US
cg.contributor.crpCGIAR Research Program on Livestock and Fish - L&Fen_US
cg.contributor.funderInternational Livestock Research Institute - ILRIen_US
cg.contributor.projectCGIAR Research Program on Livestock & Fishen_US
cg.contributor.project-lead-instituteInternational Center for Agricultural Research in the Dry Areas - ICARDAen_US
cg.coverage.regionEastern Africaen_US
dc.identifier.statusLimited accessen_US

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