dc.contributor | Hajaji, Soumaya | en_US |
dc.contributor | Rekik, Mourad | en_US |
dc.contributor | Abidi, Amel | en_US |
dc.contributor | Gharbi, Mohamed | en_US |
dc.contributor | Akkari, Hafidh | en_US |
dc.creator | Alimi, Dhouha | en_US |
dc.date.accessioned | 2017-03-14T21:51:28Z | |
dc.date.available | 2017-03-14T21:51:28Z | |
dc.identifier | https://mel.cgiar.org/dspace/limited | en_US |
dc.identifier | https://www.sciencedirect.com/science/article/pii/S0304401716303648?via%3Dihub | en_US |
dc.identifier.citation | Dhouha Alimi, Soumaya Hajaji, Mourad Rekik, Amel Abidi, Mohamed Gharbi, Hafidh Akkari. (15/9/2016). First report of the in vitro nematicidal effects of camel milk. Veterinary Parasitology, 228, pp. 153-159. | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.11766/6480 | |
dc.description.abstract | Antipathogenic properties of camel milk have been investigated to substitute for drugs hence overcome
drug resistance. The main objective of this present study was to investigate the anthelmintic activity of
camel milk in relationship to its chemical composition. In vitro anthelmintic effects of camel milk against
Haemonchus contortus from sheep were ascertained by egg hatching and worm motility inhibitions in
comparison to milks from cow, ewe and goat as well as a reference drug albendazole. Chemical composition
revealed that camel milk has higher contents of protective protein (lactoferrin) and vitamin C than
other species’ milk. It showed ovicidal activity at all tested concentrations and completely inhibited egg
hatching at a concentration close to 100 mg/mL (inhibitory concentration (IC50) = 42.39 mg/mL). Camel
milk revealed in vitro activity against adult parasites in terms of the paralysis and/or death of the worms
at different hours post treatment. After 8 h of exposure, it induced 100% mortality at the highest tested
concentration. There was 82.3% immobility of worms in albendazole 8 h post-exposition. No such effects
were seen with the other species’ milks. Bioactive compounds such as lactoferrin and vitamin C may be
involved in such an effect.
To our knowledge, these results depict for the first time that camel milk possesses in vitro anthelmintic
properties and further in vitro and in vivo trials against different parasite species and stages are required
to make use of this milk for the control of gastrointestinal nematode parasites | en_US |
dc.format | PDF | en_US |
dc.language | en | en_US |
dc.publisher | Elsevier | en_US |
dc.source | Veterinary Parasitology;228,(2016) Pagination 153-159 | en_US |
dc.subject | motility inhibition | en_US |
dc.title | First report of the in vitro nematicidal effects of camel milk | en_US |
dc.type | Journal Article | en_US |
dcterms.available | 2016-09-05 | en_US |
dcterms.extent | 153-159 | en_US |
dcterms.issued | 2016-09-15 | en_US |
cg.creator.id | Rekik, Mourad: 0000-0001-7455-2017 | en_US |
cg.subject.agrovoc | agriculture | en_US |
cg.subject.agrovoc | camel milk | en_US |
cg.subject.agrovoc | egg hatching | en_US |
cg.subject.agrovoc | haemonchus contortus | en_US |
cg.contributor.center | International Center for Agricultural Research in the Dry Areas - ICARDA | en_US |
cg.contributor.center | Manouba University, National School of Veterinary Medicine of Sidi Thabet - ENMV | en_US |
cg.contributor.center | Manouba University - UMA | en_US |
cg.contributor.crp | CGIAR Research Program on Dryland Systems - DS | en_US |
cg.contributor.funder | CGIAR System Organization - CGIAR | en_US |
cg.contributor.project-lead-institute | International Center for Agricultural Research in the Dry Areas - ICARDA | en_US |
cg.date.embargo-end-date | Timeless | en_US |
cg.coverage.region | Northern Africa | en_US |
cg.coverage.country | TN | en_US |
cg.contact | hafidh_akkari@yahoo.fr | en_US |
cg.identifier.doi | https://dx.doi.org/10.1016/j.vetpar.2016.09.003 | en_US |
cg.isijournal | ISI Journal | en_US |
dc.identifier.status | Timeless limited access | en_US |
mel.impact-factor | 2.422 | en_US |
cg.issn | 0304-4017 | en_US |
cg.journal | Veterinary Parasitology | en_US |
cg.volume | 228 | en_US |