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dc.contributorSreeramulu, Kurubaen_US
dc.contributorSharma, Hari C.en_US
dc.creatorAkbar, Mohammad S.en_US
dc.identifier.citationMohammad S. Akbar, Kuruba Sreeramulu, Hari C. Sharma. (18/6/2016). Monitoring biosafety of pharmaceutical drugs, insecticides, and other bioactive molecules to mitochondria. Atlas of Science, /, pp. 1-3.en_US
dc.description.abstractMitochondria are large cell organelles in plant and animal cells. They convert chemical energy from food in the cell to usable energy using oxygen. This process is called oxidative phosphorylation, which takes place inside the mitochondria. Reactions of Krebs cycle produce a chemical, NADH (Nicotinamide Adenine Dinucleotide, reduced form), which is then used by enzymes present in the inner mitochondrial membrane to generate energy rich adenosine triphosphate (ATP) molecules. These molecules are utilized by the cells whenever energy is required. Therefore, mitochondria are also referred as power houses of the cell. Mitochondria are abundantly present in muscle and brain cells, and sperms to supply ATPs during demand for energy. Monitoring biosafety of pharmaceutical drugs, insecticides, and other bioactive molecules to mitochondria is necessary because some of them interact with the mitochondrial membrane or membrane proteins, thereby affecting the energy levels of cells or even induces mitochondrialdependent apoptosis (programmed cell death).en_US
dc.publisherAtlas of Scienceen_US
dc.sourceAtlas of Science;/,(2016) Pagination 1,3en_US
dc.subjectmonitoring biosafetyen_US
dc.subjectpharmaceutical drugsen_US
dc.subjectbioactive moleculesen_US
dc.titleMonitoring biosafety of pharmaceutical drugs, insecticides, and other bioactive molecules to mitochondriaen_US
dc.typeJournal Articleen_US
cg.contributor.centerInternational Crops Research Institute for the Semi-Arid Tropics - ICRISATen_US
cg.contributor.centerGulbarga Universityen_US
cg.contributor.crpCRP on Grain Legumes - GLen_US
cg.contributor.funderNot Applicableen_US
cg.coverage.regionSouthern Asiaen_US
dc.identifier.statusOpen accessen_US

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