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dc.contributorGarcia Oliveira, Ana Luisaen_US
dc.contributorMenkir, Abebeen_US
dc.contributorOlawale Adetimirin, Prof. Victoren_US
dc.contributorGedil, Melakuen_US
dc.creatorGebremeskel, Saraen_US
dc.date2018-01-01en_US
dc.date.accessioned2019-05-04T13:23:42Z
dc.date.available2019-05-04T13:23:42Z
dc.identifierhttps://mel.cgiar.org/dspace/limiteden_US
dc.identifierhttps://cgspace.cgiar.org/handle/10568/89725en_US
dc.identifierhttp://dx.doi.org/10.1016/j.jcs.2017.09.001en_US
dc.identifier.citationSara Gebremeskel, Ana Luisa Garcia Oliveira, Abebe Menkir, Prof. Victor Olawale Adetimirin, Melaku Gedil. (1/1/2018). Effectiveness of predictive markers for marker assisted selection of pro-vitamin A carotenoids in medium-late maturing maize (Zea mays L. ) inbred lines. Journal of Cereal Science, 79, pp. 27-34.en_US
dc.identifier.urihttps://hdl.handle.net/20.500.11766/9923
dc.description.abstractDevelopment of pro-vitamin A (PVA) biofortified staple crops has been promoted as an option for addressing vitamin A deficiency in humans. Recently, crtRBI, lcyE and zep1 genes of carotenoid biosynthesis pathway have been identified as contributors to PVA accumulation in maize endosperm. High phenotyping cost and narrow genetic base for these nutritionally important compounds have been regarded as the major challenges. We evaluated the fidelity of existing functional markers along with new markers for PVA carotenoids and assessed the diversity of 108 maize inbreds using SSR markers. Among the existing markers, crtRB1-5′TE and crtRB1-3′TE exhibited highly significant association with PVA whereas marker Zep-SNP(801), developed in this study, was associated only with α-carotene. Collectively, a substantial improvement in the PVA content, including β-carotene, was observed with increased number of total favourable alleles. Cluster analysis based on SSR produced two major groups, each with three and two sub-groups, respectively. The inbreds containing favourable alleles of the functional markers were present in all sub-groups. Finally, this genetically diverse inbreds with high PVA can be used in breeding programme using marker-assisted selection to enhance PVA content in maize hybrids and cultivars developed for lowlands in sub-Saharan Africa.en_US
dc.languageenen_US
dc.publisherElsevier (12 months)en_US
dc.rightsCC-BY-NC-4.0en_US
dc.sourceJournal of Cereal Science;79,(2017) Pagination 27,34en_US
dc.subjectssren_US
dc.subjectdiversityen_US
dc.subjectpro vitamin aen_US
dc.subjectMaizeen_US
dc.titleEffectiveness of predictive markers for marker assisted selection of pro-vitamin A carotenoids in medium-late maturing maize (Zea mays L.) inbred linesen_US
dc.typeJournal Articleen_US
cg.creator.ID0000-0002-6258-6014en_US
cg.creator.ID-typeORCIDen_US
cg.subject.agrovocmarker assisted selectionen_US
cg.subject.agrovocmaizeen_US
cg.contributor.centerPan African University Life and Earth Science Institute - PAULESIen_US
cg.contributor.centerInternational Institute of Tropical Agriculture - IITAen_US
cg.contributor.centerUniversity of Ibadan - UI Nigeriaen_US
cg.contributor.crpCRP on Grain Legumes and Dryland Cereals - GLDCen_US
cg.contributor.funderCGIAR System Office - CGIAR - Sysen_US
cg.contributor.project-lead-instituteCRP on Dryland Systems - DSen_US
cg.date.embargo-end-dateTimelessen_US
cg.coverage.regionWestern Africaen_US
cg.coverage.countryNGen_US
cg.contactm.gedil@cgiar.orgen_US
dc.identifier.statusTimeless limited accessen_US


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