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dc.contributorSudini, Hari kishanen_US
dc.contributorUpadhyaya, Hari D.en_US
dc.contributorVarshney, Rajeeven_US
dc.contributorPandey, Manish Ken_US
dc.creatorPandey, Arunen_US
dc.date2019-11-27en_US
dc.date.accessioned2020-02-11T11:28:10Z
dc.date.available2020-02-11T11:28:10Z
dc.identifierhttps://mel.cgiar.org/reporting/download/hash/b4c03bd164d9d23daf338fdc95f99452en_US
dc.identifier.citationArun Pandey, Hari kishan Sudini, Hari D. Upadhyaya, Rajeev Varshney, Manish K Pandey. (27/11/2019). Hypoallergen Peanut Lines Identified Through Large-Scale Phenotyping of Global Diversity Panel: Providing Hope Toward Addressing One of the Major Global Food Safety Concerns. Frontiers in Genetics, 1177(10), pp. 1-15.en_US
dc.identifier.urihttps://hdl.handle.net/20.500.11766/10712
dc.description.abstractPeanut allergy is one of the serious health concern and affects more than 1% of the world’s population mainly in Americas, Australia, and Europe. Peanut allergy is sometimes life-threatening and adversely affect the life quality of allergic individuals and their families. Consumption of hypoallergen peanuts is the best solution, however, not much effort has been made in this direction for identifying or developing hypoallergen peanut varieties. A highly diverse peanut germplasm panel was phenotyped using a recently developed monoclonal antibody-based ELISA protocol to quantify five major allergens. Results revealed a wide phenotypic variation for all the five allergens studied i.e., Ara h 1 (4–36,833 μg/g), Ara h 2 (41–77,041 μg/g), Ara h 3 (22–106,765 μg/g), Ara h 6 (829–103,892 μg/g), and Ara h 8 (0.01–70.12 μg/g). The hypoallergen peanut genotypes with low levels of allergen proteins for Ara h 1 (4 μg/g), Ara h 2 (41 μg/g), Ara h 3 (22 μg/g), Ara h 6 (829 μg/g), and Ara h 8 (0.01 μg/g) have paved the way for their use in breeding and genomics studies. In addition, these hypoallergen peanut genotypes are available for use in cultivation and industry, thus opened up new vistas for fighting against peanut allergy problem across the world.en_US
dc.formatTXTen_US
dc.languageenen_US
dc.publisherFrontiers Mediaen_US
dc.rightsCC-BY-NC-4.0en_US
dc.sourceFrontiers in Genetics;1177,(2019) Pagination 1,15en_US
dc.subjectenzyme-linked immunosorbent assayen_US
dc.subjectreference seten_US
dc.subjectpeanut allergensen_US
dc.subjectara h 1en_US
dc.subjectara h 2en_US
dc.subjectara h 3en_US
dc.subjectara h 6en_US
dc.subjectara h 8en_US
dc.subjectGroundnuten_US
dc.titleHypoallergen Peanut Lines Identified Through Large-Scale Phenotyping of Global Diversity Panel: Providing Hope Toward Addressing One of the Major Global Food Safety Concernsen_US
dc.typeJournal Articleen_US
cg.creator.idPandey, Manish K: 0000-0002-4101-6530en_US
cg.creator.ID-typeORCIDen_US
cg.contributor.centerInternational Crops Research Institute for the Semi-Arid Tropics - ICRISATen_US
cg.contributor.crpCRP on Grain Legumes and Dryland Cereals - GLDCen_US
cg.contributor.funderMars Wrigley Confectioneryen_US
cg.contributor.projectIdentification of Markers and Genomic Regions Associated with Aflotoxin Resistance in Peanuten_US
cg.contributor.project-lead-instituteInternational Crops Research Institute for the Semi-Arid Tropics - ICRISATen_US
cg.coverage.regionSouthern Asiaen_US
cg.coverage.countryINen_US
cg.contactM.Pandey@cgiar.orgen_US
cg.identifier.doihttps://dx.doi.org/10.3389/fgene.2019.01177en_US
dc.identifier.statusOpen accessen_US
mel.impact-factor3.517en_US


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