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dc.contributorRtibi, Kaisen_US
dc.contributorB'chir, Fatmaen_US
dc.contributorDarghouth, Mohamed Azizen_US
dc.contributorGharbi, Mohameden_US
dc.creatorAkkari, Hafidhen_US
dc.identifier.citationHafidh Akkari, Kais Rtibi, Fatma B'chir, Mohamed Aziz Darghouth, Mohamed Gharbi. (30/9/2014). In vitro evidence that the pastoral Artemisia campestris species exerts an anthelmintic effect on Haemonchus contortus from sheep. Veterinary Research Communications, 28 (3), pp. 249-255.en_US
dc.description.abstractOccurrence of anthelmintic resistant strains of helminths is increasing. The aim of this study was to evaluate the in vitro anthelmintic activity of Artemisia campestris in comparison to albendazole against Haemonchus contortus of sheep. In this respect, in vitro anthelmintic activities of crude aqueous and crude ethanolic extracts of aerial parts of A. campestris were investigated on eggs and adults of Haemonchus contortus. Chemical analyses revealed that overall profile of both extracts samples were dominated by flavonoids among them quercetin and apigenin derivatives were the most abundant phenolics constituents. Both extract types completely inhibited egg hatching at a concentration close to 2 mg/ml. Lethal concentration 50% of A. campestris ethanolic and aqueous extracts were 0.83 and 1.00 mg/ml respectively (p<0.05). The ethanolic extract showed better in vitro activity against adult parasites than the aqueous extract in terms of the paralysis and/or death of the worms at different hours posttreatment. Dose dependent activity was also observed for both extract. After 8 and 24 h of exposure, the ethanolic extract induced 91.3 and 100% mortality at the highest tested concentration respectively, while the aqueous extract induced 3.22 and 70.96% at the same concentration respectively. To our knowledge, these results depict for the first time that A. campestris possesses in vitro anti-Haemonchus contortus propertiesen_US
dc.publisherSpringer Verlag (Germany)en_US
dc.sourceVeterinary Research Communications;28,(2014) Pagination 249-255en_US
dc.titleIn vitro evidence that the pastoral Artemisia campestris species exerts an anthelmintic effect on Haemonchus contortus from sheepen_US
dc.typeJournal Articleen_US
cg.subject.agrovocartemisia campestrisen_US
cg.subject.agrovochaemonchus contortusen_US
cg.contributor.centerThe Institution of Research and Higher Agricultural Education - IRESAen_US
cg.contributor.centerManouba University, National School of Veterinary Medicine of Sidi Thabet - ENMVen_US
cg.contributor.centerManouba University - UMAen_US
cg.contributor.centerUniversity of Jendouba, Higher Institute of Biotechnology of Beja - UJ - ISBBen_US
cg.contributor.crpCGIAR Research Program on Dryland Systems - DSen_US
cg.contributor.funderNot Applicableen_US
cg.contributor.project-lead-instituteInternational Center for Agricultural Research in the Dry Areas - ICARDAen_US
cg.coverage.regionNorthern Africaen_US
cg.isijournalISI Journalen_US
dc.identifier.statusLimited accessen_US
cg.journalVeterinary Research Communicationsen_US

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